Neighborhood guide
Tupelo, Mississippi
The region's hub for jobs, healthcare and shopping
37,923People (2020 Census)
BTupelo Public Schools, 2026
In townTupelo Regional Airport
38801 · 38804Main ZIP codes
Schools
The Tupelo Public School District serves most of the city, with Tupelo High School as its high school. It earned a B in the 2025–26 ratings under the state's new, tougher standards, after an A the year before. Some neighborhoods are zoned to the Lee County School District (rated C for 2025–26). Satellite campuses of Ole Miss, Itawamba Community College and Mississippi University for Women are in town.
Everyday conveniences
Tupelo is home to North Mississippi Medical Center, the largest non-metropolitan hospital in the country, plus the area's widest choice of shopping, restaurants and services. The 10,000-seat Huntington Bank Arena hosts concerts and events, and Toyota's Blue Springs plant is a short drive away.
Getting around
Interstate 22 connects Tupelo to Memphis and Birmingham. U.S. Highways 45, 78 and 278 and the Natchez Trace Parkway all run through the city.
Nearest airports
Tupelo Regional (TUP) is in town, with Contour Airlines flights to Nashville and Dallas/Fort Worth. Memphis International (MEM) is about 105 miles west on I-22.
Good to know
Tupelo is the birthplace of Elvis Presley, and his childhood home is open to visitors. The city is also headquarters of the Natchez Trace Parkway. The Tupelo area has about 140,000 people.
Population from the 2020 U.S. Census. School grades are the Mississippi Department of Education's 2025–26 district ratings, released October 15, 2026. Drive distances are approximate. Facts checked October 2026; ask us for the latest.